Long-term results of surgical treatment of patients with renal cell carcinoma

R.O. Zelenskiy

Abstract


Background. Among oncourological diseases, renal cell carcinoma (RCC) ranks third after bladder and prostate cancer, and is in the first place by mortality. According to different authors, approximately 30–50 % of patients develop metachronic metastases at different terms after nephrectomy. The purpose was the analysis of long-term results of surgical treatment of patients with renal cell carcinoma. Materials and methods. 120 patients participated in the study. Among them 56 women (46.6 %) and 64 (53.4 %) men, the average age was 66.3 ± 1.8 years. The prospective analysis included 95 (79.1 %) patients with a local form of RCC and 25 (20.9 %) patients with locally advanced form of RCC, 60 patients with disseminated form were included in the retrospective analysis. Results. Long-term results of surgical and combined treatment of 120 patients demonstrated disease progression in 31.6 % of patients. Conclusions. The median term of recurrence-free period exceeded 9.0 ± 1.1 months in the group of patients who underwent preoperative embolization of renal artery. In the group of patients with typical radical nephrectomy, the non-recurrence period was 5.3 ± 0.2 months. Increasing tumor anaplasia (GIII) resulted in a decrease in the duration of a non-recurring period, with an average life expectancy of 6–12 months, and only 12 (10 %) patients in this cohort had a life span of more than 2 years.

Keywords


renal cell carcinoma; preoperative embolization of vascular pedicle; long-term results

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DOI: https://doi.org/10.22141/2224-0586.8.87.2017.121338

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