Analysis of non-surgical complications in patients with implanted left ventricular assist devices

O.P. Mazurenko, P. Nadzyakevych, O.A. Loskutov, L.V. Zgrzheblovskaya


The work deals with the study of infectious, nephrotic, neurological and other complications in the early postoperative period in 10 patients with implanted left ventricular assist devices. The most common non-surgical complications include infections, ischemic hemorrhagic lesions of the brain, acute renal failure that arise in the postoperative period. Conducting optimal antithrombotic therapy in such patients is an important method of treatment, especially in the early postoperative period. Most infectious complications develop in the implanted device driveline exit site. An individual approach to preventive strategies is critical for improving patient outcomes. This article presents an analysis of complications that developed in the early postoperative period in 10 patients with implanted left ventricular assist devices of the Silesian Center for Heart Disease (Poland). Patients were divided into 2 groups: the control group receiving classical anticoagulant targeted therapy, which included heparin, warfarin and aspirin, and the study group receiving an alternative anticoagulant targeted therapy that consisted of clopidogrel, thrombin inhibitors in combination with classical anticoagulant targeted therapy.


left ventricular assist device; anticoagulant targe­ted therapy; infectious, nephrotic, pulmonary, ischemic he­morrhagic complications


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