Vitamin D and burn injury

Authors

DOI:

https://doi.org/10.22141/2224-0586.16.6.2020.216504

Keywords:

vitamin D, cholecalciferol, ergocalciferol, vitamin D Deficiency, burns, burn injury, sepsis, review

Abstract

The Deficiency of vitamin D is common in the gene­ral population. It is also noted in 40–70 % of critical patients in the intensive care units. Vitamin D has a wide range of pleiotropic effects on various processes and systems, including the immune-inflammatory response. Low level of vitamin D in critical patients is associated with more frequent Development of sepsis, respiratory Distress syndrome, multiple organ failure, and increased mortality. The clinical understanding of hypovitaminosis D remains underestimated and therefore is often ignored in acute clinical situations, including burn injury, in which several factors contribute to the Development and long-term maintenance of vitamin D Deficiency. Although studies on the level of vitamin D in burn patients are limited, vitamin D levels have been shown to Decline after thermal injury. Clarification of the current understanding of the role of vitamin D in patients with thermal injury, the effect of vitamin D level on treatment outcomes at Different periods of burn Disease, and the possibility and necessity of correcting of hypovitaminosis D in this category of patients is the goal of this review. The article analyzes the possibility of improving the results of the treatment of burn injury, preventing several complications of burn Disease by correcting the level of vitamin D.

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Published

2020-09-01

Issue

Section

Scientific Review