Assessment of myocardium impairment in coronary stenting according to the results of the analysis of electrocardiogram changes and heart rate variability

Authors

  • O.O. Syvoraksha Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine
  • I.A. Chaikovskyi Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine; VM Glushkov Institute of Cybernetics of NAS of Ukraine, Kyiv, Ukraine
  • Ya.A. Antoniuk SE “Institute of Heart of MH of Ukraine”, Kyiv, Ukraine
  • D.O. Dziuba Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine
  • O.A. Kryvova VM Glushkov Institute of Cybernetics of NAS of Ukraine, Kyiv, Ukraine
  • O.A. Loskutov Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0586.17.2.2021.230654

Keywords:

electrocardiography, coronary stenting, scaling, myocardium impairment

Abstract

Background. With every passing year, the morta-lity from cardiovascular diseases is increasing. One of the treatment methods is X-ray endovascular plasty and coronary sten-ting. However, the X-ray endovascular plasty by itself inevitably causes at least minimal impairment of coronary vessels and myocardium. The study aimed at the assessment of small electrocardiography changes using an original method of scaling immediately after the procedure of coronary stenting. Materials and methods. The study was performed in 2020 based on ES “Institute of Heart of MH of Ukraine”. Twenty-three patients were examined before coronary stenting. This investigation included pair measurements, particularly electrocardiography registration within 3 min before and after (in several hours) the surgical intervention. The examination was performed using hardware-software complex “Cardio+P”. Total of 23 pairs of electrocardiograms were analyzed. Two hundred and forty primary and measurement parameters of electrocardiography were analyzed in each electrocardiogram. Results. The results of electrocardiographic investigation allowed determining a subgroup with significant myocardium impairments. This subgroup included the patients elder compared to the rest patients. In this subgroup, the average number of stents was higher and the patients demonstrated worsened index of the psychoemotional condition along with the electrocardiogram changes.

References

Movsisyan N.K., Vinciguerra M., Medina-Inojosa J.R., Lopez-Jimenez F. Cardiovascular Diseases in Central and Eastern Europe: A Call for More Surveillance and Evidence-Based Health Promotion. Annals of Global Health. 2020. 86(1).

Benjamin E.J., Virani S.S., Callaway C.W., Chamberlain A.M., Chang A.R., Cheng S. et al. Heart Disease and Stroke Statistics — 2018 Update: A Report From the American Heart Association. Circulation. 2018. 137(12). 67-492.

Virani S.S., Alonso A., Benjamin E.J., Bittencourt M.S., Callaway C.W. et al. Heart disease and stroke statistics — 2020 update: a report from the American Heart Association. Circulation. 2020. 139-596.

Aktualni problemy zdorov’ya ta minimizatsiya yikh v umovakh zbroynogo konfliktu v Ukrayini. Ed. by V.M. Kovalenko, V.M. Kornatskiy. K.: SPD FO «Kolomitsyn V.Yu.», 2018. 214 p.

Tsentr medstatystyky — Statystychni dani [Internet]. Medstat.gov.ua. 2019 [cited 29 July, 2019]. Available from: http://medstat.gov.ua/ukr/statdan.html

Kim M.S., Dean L.S. In-stent restenosis. Cardiovasc. Ther. 2011. 29. 190-198.

Warren S.G., Wagner G.S., Bethea C.F., Roe C.R., Oldham H.N., Kong Y. Diagnostic and prognostic significance of electrocardiographic and CPK isoenzyme changes following coronary bypass surgery: correlation with findings at one year. Am. Heart J. 1977 Feb. 93(2). 189-196. doi: 10.1016/s0002-8703(77)80310-4. PMID: 299973.

Sethi S.S., Singh A., Farkouh M.E. Periprocedural myocardial enzyme elevation: prognostic implications for current practice. Curr. Cardiol. Rep. 2012 Aug. 14(4). 424-432. doi: 10.1007/s11886-012-0288-4. PMID: 22673863.

Gómez-Hospital J.A., Cequier A., Valero J., González-Costello J., Mañas P. et al. Minor myocardial damage during percutaneous coronary intervention does not affect long-term prognosis. Rev. Esp. Cardiol. 2009 Jun. 62(6). 625-632. English, Spanish. doi: 10.1016/s1885-5857(09)72226-1. PMID: 19480758.

Saadeddin S.M., Habbab M.A., Sobki S.H., Ferns G.A. Biochemical detection of minor myocardial injury after elective, uncomplicated, successful percutaneous coronary intervention in patients with stable angina: clinical outcome. Ann. Clin. Biochem. 2002 Jul. 39(Pt 4). 392-397. doi: 10.1258/000456302760042155. PMID: 12117443.

Babu G.G., Walker J.M., Yellon D.M., Hausenloy D.J. Peri-procedural myocardial injury during percutaneous coronary intervention: an important target for cardioprotection. Eur. Heart J. 2011 Jan. 32(1). 23-31. doi: 10.1093/eurheartj/ehq393. Epub 2010, Oct 29. PMID: 21037252.

Wang T.Y., Peterson E.D., Dai D., Anderson H.V., Rao S.V., Brindis R.G., Roe M.T. National Cardiovascular Data Registry. Patterns of cardiac marker surveillance after elective percutaneous coronary intervention and implications for the use of periprocedural myocardial infarction as a quality metric: a report from the National Cardiovascular Data Registry (NCDR). J. Am. Coll. Cardiol. 2008, May 27. 51(21). 2068-2074. doi: 10.1016/j.jacc.2008.01.054. PMID: 18498965.

Warren S.G., Wagner G.S., Bethea C.F., Roe C.R., Oldham H.N., Kong Y. Diagnostic and prognostic significance of electrocardiographic and CPK isoenzyme changes following coronary bypass surgery: correlation with findings at one year. Am. Heart J. 1977 Feb. 93(2). 189-196. doi: 10.1016/s0002-8703(77)80310-4. PMID: 299973.

Califf R.M., Abdelmeguid A.E., Kuntz R.E., Popma J.J., Davidson C.J., Cohen E.A. et al. Myonecrosis after revascularization procedures. J. Am. Coll. Cardiol. 1998 Feb. 31(2). 241-251. doi: 10.1016/s0735-1097(97)00506-8. PMID: 9462562.

Chaikovsky I. Electrocardiogram scoring beyond the routine analysis: subtle changes matters. Expert Review of Medical Devices. 2020. 17(5). 379-382.

US10512412В2. Chaikovsky I., Starynska G., Budnyk M. 2020: Method of ECG evaluating based on universal scoring system.

Colan S.D. Thy Way and How of Z-Scores. JASE. 2013. 26(1). 38-40.

Chaikovsky I. Kryvova O., Kazmirchuk A. et al. Assessment of the Post-Traumatic Damage of Myocardium in Patients with Combat Trauma Using a Data Mining Analysis of an Electrocardiogram. 2019 Signal Processing Symposium (SPSympo), Krakow, Poland, 2019. 34-38.

Chaikovsky I., Oshlianska O., Artsymovych A., Kryvova O., Kovalenko O., Stadniuk L. Using of Data Mining methods to evaluate the myocardial damage in children with juvenile idiopathic arthritis. 2020 IEEE 40th International Conference on Electronics and Nanotechnology (ELNANO), Kyiv, Ukraine, 2020. 391-395.

Apykhtin K., Chaikovsky I., Yaroslavskya S. et al. Adaptation of cardiovascular system to work in the night shifts of doctors and nurses. Journal of the American College of Cardiology. 2018. 72 (Suppl. 16). 243.

Neary J.P., Baker T., Jamnik V. Chaikovsky I. et al. Multimodal Approach to Cardiac Screening of Elite Ice Hockey Players During the NHL Scouting Combine. Medicine & Science in Sports & Exercise. 2014. 46. 742.

Chaikovsky I., Lebedev E., Ponomarev V., Necheporuk A. The relationship between ECG/HRV variables and socio-economic factors: results of mass screening in the rural region of Ukraine. European Journal of Preventive Cardiology. 2020. 27(1, Suppl.). 92.

Clarke R., Chaikovsky I., Wright N. et al. Independent relevance of left ventricular hypertrophy for risk of ischaemic heart disease in 25,000 adults. European Heart Journal. Nov 2020. Vol. 41. Is. Suppl. 2. ehaa946.2938. https://doi.org/10.1093/ehjci/ehaa946.2938.

Боровиков В.С. STATISTICA. Искусство анализа данных на компьютере. СПб.: Питер, 2003. 688 с.

Мандель И.Д. Кластерный анализ. М.: Финансы и статистика, 1988. 176 с.

Published

2021-05-24

Issue

Section

Original Researches