Modern Local Anesthetics Used for Neuraxial Anesthesia

Kim Yen-Din, A.A. Semenikhin, A.K. Abidov, A.F. Ilkhamov, Ye.A. Besschetnova, B.I. Makhkamov, N.M. Kamalova, N.K. Shodmankulova


The study was conducted involving 63 pregnant women and obstetric patients aged 18–40 years. According to the type of continuous epidural analgesia (CEAn), all pregnant women were divided into two groups: I (n = 31), CEAn was performed using 1.5% lidocaine (1 mg/kg), in group II (n = 32) CEAn was carried out by means of 0.25% Longocain (0.25–0.3 mg/kg). Sensometry was carried our using galvanizer «Potok-1», GE-50-2. We have determined tactile and pain threshold, the threshold of endurance. The studies have shown that 0.25% Longocain significantly blocks pain afferent impulses in the area of segmental blockade without severe motor blockade compared with 1.5% lidocaine, and completely eliminates the pain in obstetric patients throughout childbirth. It is safe for the mother, the fetus and the newborn in the early period of adaptation.


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