Rationale for the Use of Regional Analgesia for Pain Relief in the Early Postoperative Period in Children with Cancer

D.V. Dmitriiev

Abstract


The study was conducted in 62 children aged 14.2 ± 4.2 years: 24 patients (38.7 %) operated for abdominal tumors, 38 (41.3 %) children — for retroperitoneal tumors. Comprehensive study of reactions of pain behavior, physiological indicators and laboratory stress tests showed that the use of regimens of combined regional analgesia with 0.375 % bupivacaine and continuous intravenous infusion of fentanyl at a dose of 10 mg/kg/h for postoperative pain relief leads to effective analgesia after traumatic cancer surgery. Multimodal analgesia — regional analgesia and continuous intravenous infusion of opioid analgesics — improves the central and mesenteric hemodynamics and may reduce the risk of complications in the postoperative period and results in a decrease of hyperalgesia manifestations, and the use of acetaminophen for additional pain relief leads to adequate analgesia, and does not affect the development of hyperalgesia unlike narcotic analgesics.


Keywords


analgesia; regional analgesia; paracetamol; children

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DOI: https://doi.org/10.22141/2224-0586.3.74.2016.77523

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