Brain Abscess: Analysis of Treatment of 242 Patients

Yu.A. Yasharov

Abstract


Rationale. Despite the rapid development of microsurgical techniques, imaging, antibiotic therapy abscesses of the brain are still potentially fatal infectious disease of the central nervous system. An important feature of this disease is that it affects people of younger working age. Objective. To analyze the efficacy of surgical treatment of brain abscesses. Materials and methods. Among 242 patients with brain abscesses there were 33 children and 209 adults. Among adults males were 143 (68.4 %), women — 66 (31.6 %). The age of patients ranged from 4 months to 74 years old, an average age was 36.5 ± 13.8 years old. Results. To assess the effectiveness of treatment and the degree of disability in patients with brain abscesses there were used Glasgow Scale (Glasgow Outcome Scale). In general, at discharge or transferring of the patients to the neurosurgical unit the following results were observed: 77 (32 %) — good recovery (5 scores); 90 (37 %) — satisfactory result (4 scores); 41 (17 %) — lack of improvement, profound disability (3 scores), 5 (2 %) —unsatisfactory result (2 scores); 29 (12 %) cases were fatal (1 score). Good results in the application of stereotaxic technology received 1.7 times oftener, namely 30.8 % at traditional neurosurgical intervention and 50 % with neuronavigation and stereotactic surgery (R < 0.05). Conclusion. Analyzing the results by the years of research, a clear tendency to reduce the percent of deaths from 20 % in 1995–1999 to 9.9 % in 2011–2014 is registered, and thus, the enhancement of number of positive results.

Keywords


brain abscess; treatment efficiency; surgical treatment

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DOI: https://doi.org/10.22141/2224-0586.3.74.2016.77587

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