Parturient’s Cognitive Functions after Caesarean Section Depending on Bispectral Index Values during General Anesthesia

O.O. Volkov


The aim of this article is to study the influence of bispectral index on parturients’ cognitive functions during total intravenous anesthesia for cesarean section. After local ethics committee approval and obtained informal consent, 32 parturients are inspected in 37–42 gestation weeks who have delivered by the caesarian section under the total intravenous anesthesia. Cognitive functions were found to be decreased till delivery or till 37th–42nd gestation week that is caused by pregnancy, It was shown cognitive functions remain significantly decreased by day 5–7 at total intravenous anesthesia. There are significant wavering in interval of BIS from 30.5 to 76.5 during total intravenous anesthesia with thiopental sodium for cesarean section. BIS index is significantly decreased during intubation. Minimal means of BIS correlated with the initial cognitive function levels. Induction dose of thiopental sodium is enough for laryngoscopy and intubation of trachea. But while extraction of fetus the BIS index values exceed allowable ones — 60. During anesthesia maintaining after fetus extraction BIS varieties significantly for awakening. Low minimal BIS index deteriorates the cognitive functions, but not memory during total intravenous anesthesia o the 5th–7th day in parturient. Increasing of thiopental sodium dose for anesthesia maintenance enhances maximal BIS means, however increasing of thiopental sodium dose for anesthesia induction correlated with low BIS maximal values. Time from intervention end to extubation directly depends on operation duration but not from thiopental sodium dose. High doses of thiopental sodium for anesthesia induction forcesarean section deteriorate cognitive functions on the 1st day after intervention.


caesarian section; bispectral index; cognitive dysfunctions, general anesthesia


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