Current Approaches to the Correction of Hemostasis in Surgeries for Giant Uterine Myoma

O.O. Tarabrin, D.H. Havrychenko, S.S. Shcherbakov, H.I. Mazurenko, O.V. Turenko, K.P. Kirpichnikova

Abstract


The objective of the study was to reduce the perioperative blood loss in patients with giant uterine myoma. As a result of studies, we have obtained evidence that the use of antifibrinolytic therapy as intravenous infusion of tranexamic acid 30 minutes before the surgery in a dose of 20 mg/kg followed by infusion of 5 mg/kg per hour for the first postoperative day helped to reduce perioperative blood loss by 29 %. In patients of the second group, hemoglobin level on the second postoperative day was higher by 10 % (p < 0.05), blood loss was lower by 29 % (p < 0.05), the length of stay in hospital was reduced by 24 % (p < 0.05).


Keywords


giant uterine myoma; blood loss; fibrinolysis

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DOI: https://doi.org/10.22141/2224-0586.8.71.2015.79203

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