Up-To-Date Technologies Reflecting Pain and Nociception

Yu.Yu. Kobeliatskyi, О.O. Shaida


Though anaesthesia has been used for a long time the monitoring of its adequacy is still challenging. New techniques based on electroencephalography analysis allow assess hypnotic effect of anaesthetic agents. However besides the loss of consciousness, adequate inhibition of subcortical brain activity should be achieved during surgical procedures. The data about possible development of opiate-induced hyperalgesia in postoperative period due to their high doses used for anaesthesia require to improve approaches to their dosages. This review considers several techniques been developed for the last decade that allow get an insight about analgesia-nociception balance according to the assessment of autonomic nervous system.


monitoring of analgesia/nociception balance; general anaesthesia; autonomic nervous system


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