Application of Gliatilin in Conservative Pharmacotherapy for Severe Traumatic Brain Injury with Cerebral Contusion

V.O. Piatykop, I.O. Kutovyi, Yu.O. Babalian, A.V. Stohnii, Yu.O. Kotliarevskyi, A.O. Pshenichnyi

Abstract


There are provided the data from a study on Gliatilin (choline alfoscerate) efficacy in the treatment of acute period of traumatic brain injury, severe brain contusion with impaired consciousness, when surgery is not indicated, but contusion foci with impaired consciousness are detected. The study included 40 patients (28 men and 12 women) aged 21 to 63 years (mean age — 42 years) with severe traumatic brain injury. Patients were divided into 2 groups of 20 people (14 men and 6 women), according to prescribed therapy. I group received standardized metabolic, antiedemic, antibiotic and nootropic therapy. II group— the same therapy with additional intravenous fluid drip administration of Gliatilin at a dose of 1000 mg/day. On the background of pharmacotherapy, we have observed its efficacy in the dynamics throughout the whole course (14 days) by Glasgow Coma Scale, according to the data of epidural intracranial pressure monitoring and spiral computed tomography of the brain.


Keywords


traumatic brain injury; treatment; Gliatilin

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DOI: https://doi.org/10.22141/2224-0586.1.64.2015.79574

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