Premenstrual Syndrome

E.B. Yakovleva, O.M. Babenko, O.N. Pilipenko


Premenstrual syndrome (PMS) — complex cyclic group of symptoms occurring in some women in premenstrual days and characterizing by psychoemotional, vegetovascular, metabolic and endocrine impairments.
Today etiopathogenic mechanisms of syndrome are poorly studied. There are many theories to explain the appearance of PMS symptoms. The most modern theory of PMS origin is the theory of neurotransmitter metabolism disturbances in the central nervous system. Depending on the prevalence of certain symptoms there are evolved four main clinical forms of the disease. Except that, depending on the number, duration, and intensity of symptoms during PMS there are distinguished the mild and severe forms of the disease’s course. Also, there are three stages of the syndrome: compensated, subcompensated and decompensated.
Due to the huge amount of PMS symptoms there are some difficulties in the diagnosis of disease. The basis for the diagnosis is cyclicity of pathological symptoms, occurring a few days before menstruation. The main therapy methods for premenstrual syndrome are pharmacotherapy, hormone therapy and non-drug treatment. If the effect of the therapy is positive, preventive supportive treatment, including vitamins and tranquilizers, is recommended.


premenstrual syndrome; women; treatment


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