Indicators of Systemic Inflammatory Response in Patients with Severe Acute Pancreatitis in Early Stage Depending on the Components of Infusion Therapy

O.I. Datsyuk


In 91 patients with severe acute pancreatitis in early stage we have studied the severity of manifestations of systemic inflammatory response and organ dysfunction/failure depending on the composition of fluid resuscitation. We have found that the addition of HES 130/0.4 solutions or solutions of polyhydric alcohols (sorbilact, rheosorbilact) to crystalloid infusion therapy in patients with severe acute pancreatitis helped to reduce manifestations of systemic inflammatory response syndrome and do not adversely affect the incidence of renal dysfunction and disorders of blood coagulation.


acute pancreatitis; systemic inflammatory response syndrome; infusion therapy


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