Indicators of Systemic Inflammatory Response in Patients with Severe Acute Pancreatitis in Early Stage Depending on the Components of Infusion Therapy
In 91 patients with severe acute pancreatitis in early stage we have studied the severity of manifestations of systemic inflammatory response and organ dysfunction/failure depending on the composition of fluid resuscitation. We have found that the addition of HES 130/0.4 solutions or solutions of polyhydric alcohols (sorbilact, rheosorbilact) to crystalloid infusion therapy in patients with severe acute pancreatitis helped to reduce manifestations of systemic inflammatory response syndrome and do not adversely affect the incidence of renal dysfunction and disorders of blood coagulation.
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De Waele J. Bloodstream infections after surgery for severe acute pancreatitis / J. De Waele, S. Blot, F. Colardyn // Pancreas. — 2004. — Vol. 28, № 4. — Р. 391-394.
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis / R.C. Bone, R.A. Balk, F.B. Cerra [et al.] // Chest. — 1992. — Vol. 101. — P. 1644-55.
Early fluid resuscitation reduces morbidity among patients with acutepancreatitis / M.G. Warndorf, J.T. Kurtzman, M.J. Bartel [et al.] // Clin. Gastroenterol. Hepatol. — 2011. — Vol. 9, № 8. — Р. 705-709.
Effects of hydroxyethyl starch 130/0.4 on pulmonary capillary leak-age and cytokines production and NF-kappaB activation in CLP-induced sepsis in rats / X. Feng, W. Yan, X. Liu [et al.] // J. Surg. Res. — 2006. — Vol. 135, № 1. — P. 129-136.
Predictors of severe and critical acutepancreatitis: A systematic review / C.J. Yang, J. Chen, A.R. Phillips [et al.] // Dig. Liver. Dis. — 2014. — Vol. 46, № 5. — Р. 446-451.
Protective roles of hydroxyethyl starch 130/0.4 in intestinal inflammatory response and survival in rats challenged with polymicrobial sepsis / X. Feng, J. Liu, M. Yu [et al.] // Clin. Chim. Acta. — 2007. — Vol. 376, № 1–2. — P. 60-67.
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