The Interrelation of Pro- and Antiinflammatory Cytokines in the Third Trimester of Pregnancy

Ye.N. Klyhunenko, A.O. Volkov

Abstract


We have found that serum IL-6 level increases in women with 37–42 weeks of gestation, but TNF-α concentration decreases. IL-10 level was upper of expected regional norm.


Keywords


pregnancy; cognitive dysfunction; cytokines

References


Spulber et al. Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain // J. Neuroimmunol. — 2009. — 208 (1-2). — 46-53.

Taishi et al. // Brain Res. — 2008. — 1226. — 89-98.

Rage et al. // Neurochem. Int. — 2006. — 49 (5). — 433-41.

Wan Y., Xu J., Ma D., Zeng Y., Cibelli M., Maze M. Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus // Anesthesio­logy. — 2007. — 106 (3). — 436-43.

Economos A., Wright C.B., Moon Y.P., Rundek T., Rabbani L., Paik M.C., Sacco R.L., Elkind M.S. Interleukin 6 plasma concentration associates with cognitive decline: the northern Manhattan study // Neuroepidemiology. — 2013. — 40 (4). — 253-9.

Gomes da Silva S., Simöes P.S., Mortara R.A., Scorza F.A., Cavalheiro E.A., da Graça Naffah-Mazzacoratti M., Arida R.M. Exercise-induced hippocampal anti-inflammatory response in aged rats // J. Neuroinflammation. — 2013. — 10. — 61.

Maes M., Ombelet W., Verkerk R., Bosmans E., Scharpé S. Effects of pregnancy and delivery on the availability of plasma tryptophan to the brain: relationships to delivery-induced immune activation and early post-partum anxiety and depression // Psychol. Med. — 2001. — 31 (5). — 847-58.




DOI: https://doi.org/10.22141/2224-0586.7.62.2014.84166

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