Optimization of the Intensive Care Strategies in Patients with Sepsis Based on Clinical and Statistical PIRO Model

L.A. Maltseva, A.V. Tsarev, O.O. Volkov, N.F. Mosensev


The variant of the clinical and statistical PIRO model created by us has haeuristic, prognostic and expert capabilities; allows on the early stages of septic process to define the outcome of the disease accurately, using basic parameters influencing the severity of the course and outcome of the disease; to establish that patients, who suffered a septic episode, had persistence organ dysfunction, the severity of proemorbid state increases, quality of life goes down, these patients require the subsequent ambulatory supervision for the prevention of the emergence, prevention of progression and treatment of persistent organ dysfunction/failure.


sepsis; multiple organ dysfunction/failure; stratification; PIRO model; treatment


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