The Prevalence of Risk Factors for Thromboembolic and Hemorrhagic Complications among Patients with Atrial Fibrillation

V.I. Tseluyko, N.A. Opolonskaya

Abstract


The paper presents the results of a study on prevalence of risk factors for thromboembolic and hemorrhagic complications in patients with non-valvular atrial fibrillation during long-term follow-up for 2 years. A detailed analysis of specific risk factors has been carried out in patients using scales CHADS2, CHA2DS2-VASc and HAS-BLED. Depending on baseline risk, we determined the incidence of endpoints (stroke, TIA, hemorrhagic complications or death from cardiovascular causes or a combination of outcomes). We established the dependence between prevalence of thromboembolic and hemorrhagic complications and the number of points by scales CHA2DS2-VASc and HAS-BLED.


Keywords


atrial fibrillation; thromboembolic and hemorrhagic complications; risk factors; scales CHADS2; CHA2DS2-VASc and HAS-BLED

References


Зотова И.В., Исаева М.Ю., Алехин М.Н. Оценка риска тромбоэмболий при мерцательной аритмии: современное состояние проблемы // Атеротромбоз. — 2013. — № 1. — С. 21-31.

Дзяк Г.В. Фибрилляции предсердий // Здоров’я України. — 2009, вересень. — С. 15-16.

Kirchhof P., Auricchio A., Bax J. Outcome parameters for trials in atrial fibrillation: executive summary // Eur. Heart J. — 2007 Nov. — 28(22). — 2803-2817.

Комаров А.Л. «Старые» и «новые» возможности профилактики инсульта у больных с фибрилляцией предсердий // Атеротромбоз. — 2013. — № 1. — С. 44-52.

Friberg L., Hammar N., Rosengvist M. Stroke in paroxysmal atrial fibrillation: Report from the Stockhom Cohort of Atrial Fibrillation // Eur. Heart J. — 2010. — Vol. 31. — P. 967-975.

Nabauer M., Gerth A., Limbourg T., Schneider S., Oeff M., Kirchhof P., Goette A., Lewalter T., Ravens U., Meinertz T., Brei­thardt G., Steinbeck G. The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management // Europace. — 2009. — 11. — 423-434.

Stroke Risk in Atrial Fibrillation Working Group. Comparison of 12 risk stratification schemes to predict stroke in patients with nonvalvular atrial fibrillation // Stroke. — 2008. — 39. — 1901-1910.

European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery, Camm A.J., Kirchhof P., Lip G.Y., Schotten U., Savelieva I., Ernst S., Van Gelder I.C., Al-Attar N., Hindricks G., Prendergast B., Heidbuchel H., Alfieri O., Angelini A., Atar D., Colonna P., De Caterina R., De Sutter J., Goette A., Gorenek B., Heldal M., Hohloser S.H., Kolh P., Le Heuzey J.Y., Ponikowski P., Rutten F.H. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC) // Eur. Heart J. — 2010 Oct. — 31(19). — 2369-429.

Lip G.Y., Nieuwlaat R., Pisters R., Lane D.A., Crijns H.J. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the Euro Heart Survey on atrial fibrillation // Chest. — 2010. — 137. — 263-272.

Apostolakis S., Lane D.A., Guo Y., Buller H.R., Lip G.Y.H. Performance of theHEMORR2HAGES, ATRIA and HAS-BLED bleeding risk prediction scores inanticoagulated patients with atrial fibrillation: The AMADEUS study // J. Am. CollCardiol. — 2012. — 60. — 861-867.

Рекомендации РКО, ВНОА, АССХ. Диагностика и лечение фибрилляции предсердий / Под ред. проф. Сулимова В.А. — М., 2012. — С. 34-36.

Cairns J.A., Connolly S., McMurtry S. et al. Canadian Cardiovascular Society atrial fibrillation guidelines 2010: prevention of stroke and systemic thrombormbolism in atrial fibrillation and flutter // Can. J. Cardiol. — 2011. — 27. — 74-90.

Camm J., Lip G.Y., Raffaele De Caterina et al. 2012 focused update of the ECS Guidelines for the management of atrial fibrillation. An update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of European Heart Rhythm Association // ECS Guidelines. — 2012. — 1-29.




DOI: https://doi.org/10.22141/2224-0586.7.54.2013.88591

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 EMERGENCY MEDICINE

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru