Role and Place of omega-3 Fatty Acids in the Regulation of Systemic Inflammatory Response Syndrome in Patients Receiving Intensive Care

N.V. Matolinets

Abstract


The paper deals with the analysis of current data on the role of ω-3 fatty acids in nutrition support of the critically ill patients, their effect on the dynamics of the systemic inflammatory response syndrome (SIRS), the compensatory anti-inflammatory response syndrome (CARS), as well as mixed antagonist response syndrome developing at interacting of diverse (inflammatory/anti-inflammatory) responses (SIRS/CARS). The application of replacement immune correction in the complex of intensive therapy of critical conditions is pathogenetically grounded and could be a component of the therapy oriented for organ protection. The presence of SIRS or CARS in patients should determine the choice of lipid emulsion in the complex of parenteral nutrition with the addition of MCT/LCT emulsions with ω-3 fatty acids in the clinic of intensive care. The usage of lipid emulsions enriched with fish oils reduces the duration of hospital treatment of the critically ill patients.


Keywords


critical conditions; cytokines; inflammation; fatty acids

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DOI: https://doi.org/10.22141/2224-0586.8.79.2016.90370

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