DOI: https://doi.org/10.22141/2224-0586.2.81.2017.99698

New hemostatic bandages based on a natural biopolymer chitosan

A.E. Feskov, A.S. Sokolov, S.V. Soloshenko

Abstract


Bleeding is deadly dangerous. Emergency, effective hemostasis is the main task in providing assistance both in civil conditions and at battlefields. Therefore, prehospital hemostatic care should be provided as soon as possible. A good hemostatic agent should be available in the emergency setting, easy to apply, and have the ability to control bleeding from great vessels. Such a solution can be a national haemostatic bandage Revul® on a nonwoven basis with chitosan that meets all the requirements for these materials. Haemostatics based on chitosan when stopping massive bleeding relates to first aid by North Atlantic Treaty Organization (NATO) classification. Therefore, a hemostatic chemical-based bandage (chitosan, etc.), according to the Tactical Combat Casualty Care guidelines, 2009, the intensive care manual for pre-hospital trauma in the combat area (Battlefild Advanced Trauma Life Support), is included in the modern NATO standard kit as an indispensable component.


Keywords


bleeding; chitosan

References


Bellamy R.F. The causes of death in conventional land warfare: implications for combat casualty care research // Mil. Med. — 1984. — 149. — 55-62.

Alam H.B., Burris D., DaCorta J.A. and Rhee P. Hemorrhage control in the battlefield: role of new hemostatic agents // Mil. Med. — 2005. — 170. — 63-69.

Starnes B.W., Beekley A.C., Sebesta J.A., Ander­sen C.A., Rush R.J. Extremity vascular injuries on the battlefield: tips for surgeons deploying to war // J. Trauma. — 2006. — 60. — ­432-442.

Walters T.J., Mabry R.L. Issues related to the use of tourniquets on the battlefield // Mil. Med. — 2005. — 170. — 770-775.

Mabry R.L., Holcomb J.B., Baker A.M., Cloonan C.C., Uhorchak J.M., Perkins D.E., Canfield A.J., Hagmann J.H. United States Army Rangers in Somalia: an analysis of combat casualties on an urban battlefield // J. Trauma. — 2000. — 49. — 515-528, 528-529.

Mendis D., Vesely M. Improvements in the management of trauma patients with the introduction of a lower limb trauma coordinator // Trauma Mon. — 2012. — 16 (4). — 201-2. doi: 10.5812/kowsar.22517464.3424. [PMC free article] [PubMed] [Cross Ref]

Calkins D., Snow C., Costello M., Bentley T.B. Evaluation of possible battlefield tourniquet systems for the far-forward setting // Mil. Med. — 2000. — 165. — 379-384.

Tan H., Ma R., Lin C., Liu Z., Tang T. Quaternized chitosan as an antimicrobial agent: antimicrobial activity, mechanism of action and biomedical applications in orthopedics // Int. J. Mol. Sci. — 2013. — 14 (1). — 1854-1869. doi: 10.3390/ijms14011854

Zhang Y.-J., Gao B., Liu X.-W. Topical and effective hemostatic medicines in the battlefield // International Journal of Clinical and Experimental Medicine. — 2015. — 8 (1). — 10-19.

Pozza M., Millner R.W.J. Celox (chitosan) for haemostasis in massive traumatic bleeding: experience in Afghanistan // Eur. J. Emerg. Med. — 2011. — 18 (1). — 31-33. doi: 10.1097/ MEJ.0b013e32833a5ee4

Carles G., Dabiri C., Mchirgui A. et al. Different uses of chitosan for treating serious obstetric hemorrhages // Gynecol. Obstet. Res. Open J. — 2016. — 3 (1). — 13-15. doi: 10.17140/GOROJ-3-129

Inaba K., Rhee P., Teixeira P.G. et al. Intracorporeal use of advanced local hemostatics in a damage control swine model of grade IV liver injury // J. Trauma — 2011. — Vol. 71, № 5. — P. 1312-1318.




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