Lidocaine in multimodal anesthesia: a panacea of the present or a new fashion trend?


  • О.A. Loskutov Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of the Ministry of Health of Ukraine”, Kyiv, Ukraine
  • T.A. Danchyna Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine National Military Medical Clinical Center “MMCH”, Kyiv, Ukraine
  • V.H. Kolesnykov Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of the Ministry of Health of Ukraine”, Kyiv, Ukraine
  • A.M. Druzhina Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of the Ministry of Health of Ukraine”, Kyiv, Ukraine



multimodal low opioid anesthesia, intravenous lidocaine, coronary bypass


The paper considers the action and the effectiveness of multimodal low-opioid anaesthesia with intravenous lidocaine in cardiac surgery. The study included 28 patients aged 69.5 ±
± 6.2 years who underwent coronary artery bypass grafting under artificial blood circulation. The patients received endotracheal anaesthesia. The induction was performed with propofol (1.52 ± 0.05 mg/kg), fentanyl (1–1.5 μg/kg), pipecuronium bromide (0.1 mg/kg), and lidocaine (1 mg/kg bolus) followed by the continuous infusion of lidocaine (1.5–2 mg/kg/h), sevoflurane (1.5–2 MAC), intravenous magnesium sulphate (30 mg/kg) and ketamine (0.5 mg/kg) once before the incision. The average dose of fentanyl used for the entire period of anesthesiology support was 1.09 ± 0.03 μg/kg/h (358.3 ± 27.1 μg for the duration of surgery). The mean pain level on visual analogue scale was 4.6 ± 1.2. At day one, 27.8 % of patients reported the maximum severity of pain, 72.2 % of individuals had medium or low pain. The offered regimen of low-opioid anaesthesia with intravenous lidocaine can ensure adequate analgesia. It allows refusing the intraoperative use of high doses of fentanyl during highly traumatic operations, as indicated by the absence of hemodynamic and endocrine-metabolic changes.


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How to Cite

Loskutov О., Danchyna, T., Kolesnykov, V., & Druzhina, A. (2021). Lidocaine in multimodal anesthesia: a panacea of the present or a new fashion trend?. EMERGENCY MEDICINE, (2.97), 82–88.



Original Researches