Scientific evidence for ascorbic acid usage in burn patients


  • A.N. Lytovchenko V.N. Karazin Kharkiv National University, Kharkiv, Ukraine
  • H.A. Oleinyk Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
  • Ye.Yu. Lytovchenko V.N. Karazin Kharkiv National University, Kharkiv, Ukraine



ascorbic acid, burns, burn shock, sepsis, fluid resuscitation


Despite significant advances in recent years, mortality due to severe thermal injury remains high. There is no ideal protocol for resuscitation in severe burn patients, and researches have shown that patients often receive more fluid than required. A significant proportion of victims with extensive burns die from sepsis and multiple organ failure. Currently, there is a search for ways to improve the results of treatment of this category of patients, both at the stage of burn shock and at the stage of septic complications. Ways to prevent sepsis and multiple organ failure are being sought. This article analyzes the literature data on the use of ascorbic acid, both in burn shock and at later stages of burn disease. The benefits of prescribing large amounts of vitamin C have been shown and justified in preventing overhydration, fluid creep, reducing capillary leakage and related complications, accelerating the healing of burn wounds, and in preventing and improving the results of treatment of sepsis in burn patients.


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How to Cite

Lytovchenko, A., Oleinyk, H., & Lytovchenko, Y. (2021). Scientific evidence for ascorbic acid usage in burn patients. EMERGENCY MEDICINE, (4.99), 145–152.



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