Impaired renal function in the acute period of burn disease and its prognostic value

Authors

  • M.G. Koval State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine Municipal Institution “Odesa Regional Сlinical Medical Center”, Odesa, Ukraine
  • O.Yu. Sorokina State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine Municipal Institution “Odesa Regional Сlinical Medical Center”, Odesa, Ukraine
  • S.V. Tatsyuk State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine Municipal Institution “Odesa Regional Сlinical Medical Center”, Odesa, Ukraine

DOI:

https://doi.org/10.22141/2224-0586.7.102.2019.180358

Keywords:

burn disease, acute kidney damage, proteinuria, serum creatinine

Abstract

Background. The purpose was to determine the effect of severe thermal injury on changes in the indicators of renal function in the acute period of burn disease. Materials and methods. A retrospective analysis of 132 patients with severe burn injury was carried out; they were divided into two groups depending on the outcome of burn disease. Results. The study involved 132 histories of patients with severe burn disease. In 5.4 % (n = 3) of patients in group I and 85.5 % (n = 65) of patients in group II, the development of acute kidney damage was observed. Also, 10.5 % (n = 8) of patients in group II had a history of chronic kidney disease. On the first day of the acute course of burn disease, there was an increase in creatinine level in group II — 84.8 ± 4.2 μmol/L that exceeded the indicators of group I, which were below the norm, — 67.9 ± ± 2.1 μmol/L. Serum urea levels were increased from the first day of burn disease in groups I and II, and reached a maximum on day 14 of the acute phase (p = 0.304 and p = 0.694), respectively. Proteinuria in the studied groups was observed from the first day of burn disease and reached a maximum on day 7 in group I (0.22 ± 0.10 g/l, p = 0.115) and on day 14 in group II (0.2 ± 0.1 g/l, p = 0.069). The rate of daily diuresis during the entire period of burn disease did not change significantly in both groups. Conclusions. The course of severe burn disease in patients is accompanied by the development of renal damage that, together with age, the degree of damage and the presence of concomitant pathologies, leads to high mortality.

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References

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Published

2021-10-01

How to Cite

Koval, M., Sorokina, O., & Tatsyuk, S. (2021). Impaired renal function in the acute period of burn disease and its prognostic value. EMERGENCY MEDICINE, (7.102), 52–55. https://doi.org/10.22141/2224-0586.7.102.2019.180358

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Original Researches

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