Antidote therapy in modern toxicological practice

Authors

  • S.M. Nedashkivskyi Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • B.S. Sheiman Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • O.A. Halushko Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • A.H. Bohomol Kyiv City Clinical Emergency Hospital, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0586.16.3.2020.203165

Keywords:

antidotes, acute poisonings, the International Programme on Chemical Safety

Abstract

The article presents modern approaches to the prescription of antidote agents for acute poisonings. Data on rational antidote therapy were collected, mechanisms of action of these drugs are considered, dosing regimens are provided, information was provided on the usefulness of prescribing drugs not only as antidotes, but also in other situations where they are considered first-line drugs and may be useful.

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References

Марков Ю.І., Недашківський С.М., Лоскутов О.А. Тлумачний словник з клінічної токсикології. Київ, 2018. 152 с.

Коновчук В.М., Власик Л.І., Акентьєв С.О., Акентьєва М.С. Гострі отруєння важкими металами: антидоти та інтенсивна терапія. Медицина неотложных состояний. 2014. № 2(57). С. 79-82.

Шейман Б.С., Борщов С.П., Недашківський С.М., Соколов М.М., Падалка В.М. НДР: Наукове обґрунтування організації медичної допомоги населенню при гострих отруєннях. Український науково-практичний центр екстреної медичної допомоги та медицини катастроф. Київ, 2008. 234 с.

Элленхорн М.Дж. Медицинская токсикология: диагностика и лечение отравлений у человека. Т. 1. Москва: Медицина, 2003. С. 91-108.

Illinois Poison Center. Antidote Stocking Chart. Uses and Suggested Minimum Stock Quantities for Poison Antidotes for Illinois Hospitals with Emergency Departments. [Інтернет]. [Лютий 2018]. Доступний у: https://www.illinoispoisoncenter.org/sites/default/files/Antidote%20Stocking%20List%20Final%202018.pdf

Lisa M. Nissen, Kai Hang Wong, Anthea Jones, Darren M. Roberts. The Australian Journal of Rural Health. Availability of antidotes for the treatment of acute poisoning in Queensland public hospitals. 2010. Р. 24.

Nicholas A. Buckley, Andrew H. Dawson, David N. Juurlink, Geoffrey K. Isbister, Fountain J.S., Sly B., MacDonell S. Availabi­lity of antidotes, antivenoms, and antitoxins in New Zealand hospital pharmacies. N Z Med. J. 2015. С. 128.

Persson H.E., Sjoberg G.K., Haines J.A., Pronczuk de Gabrino J. Poisoning severity score. Grading of acute poisoning. J. Toxicol. Clin. Toxicol. 1998. № 3. Р. 205-13.

Ruben H.K. Thanacoody, Gloria Aldridge, Willie Laing, Paul I. Dargan, Stephen Nash, John P. Thompson, Allister Vale et al. National audit of antidote stocking in acute hospitals in the UK. Emergency Medicine Journal. 2013. Vol. 30. Is. 5.

Published

2020-05-28

How to Cite

Nedashkivskyi, S., Sheiman, B., Halushko, O., & Bohomol, A. (2020). Antidote therapy in modern toxicological practice. EMERGENCY MEDICINE, 16(3), 47–55. https://doi.org/10.22141/2224-0586.16.3.2020.203165

Issue

Section

Practicing Physician

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