Cocaine intoxication


  • S.V. Kursov Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine



cocaine, drug poisoning


Acute poisonings with psychostimulating drugs are frequent in modern society. Cocaine is a fairly common drug that has a powerful stimulating effect on the central nervous system, as well as a local anesthetic effect. This lecture is devoted to the problem of cocaine intoxication and its treatment at the prehospital and hospital stages.


Download data is not yet available.


American Heart Association. Web-based Integrated 2010 & 2015 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 10: Special Circumstances of Resuscitation [Guideline, accessed: June 29, 2018]. Available from:

Burnett L.B. Cocaine Toxicity Treatment & Management [Internet]. Medscape: Drugs & Diseases [Updated: Sep 01, 2018]. Available from:

Callaway C.W., Clark R.F. Hyperthermia in Psychostimulant Overdose. Annals of Emergency Medicine. 1994. Vol. 24. № 1. Р. 68-76.

Stahelin L., de Magalhães Souza Fialho S.C., Neves F.S. [et al.]. Cocaine-induced Midline Destruction Lesions with Positive ANCA Test Mimicking Wegener's Granulomatosis. Revista Brasileira de Reumatologia. 2012. Vol. 52. № 3. Р. 531-437. Available from:

Qureshi A., Suri M.F., Guterman L.R. [et al.]. Cocaine Use and the Likelihood of Nonfatal Myocardial Infarction and Stroke: Data from the Third National Health and Nutrition Examination Survey. Circulation. 2001. Vol. 103. № 4. P. 502-506. Available from:

Agrawal P.R., Scarabelli T.M., Saravolatz L. [et al]. Current strategies in the evaluation and management of cocaine-induced chest pain. Cardiology Reviews. 2015. Vol. 23. № 6. Р. 303-311.

Foundation for a Drug-Free World International. The True about Cocaine: Cocaine: a Short History [Internet]. Foundation for a Drug-Free World International [Accessed: November 2008]. Availab­le from:

Hantson P. Mechanisms of toxic cardiomyopathy. Clinical Toxicology (Phila). 2019. Vol. 57. № 1. Р. 1-9.

Havakuk O., Rezkalla S.H., Kloner R.A. The Cardiovascular Effects of Cocaine. Journal of the American College of Cardiology. 2017. Vol. 70. № 1. P. 101-113. Available from:

Laskowski L.K., Landry A., Vassallo S.U. [et al.]. Ice Water Submersion for Rapid Cooling in Severe Drug-Induced Hyperthermia. Clinical Toxicology (Phila). 2015. Vol. 53. № 3. Р. 181-184. doi: 10.3109/15563650.2015.1009994

Pramanik P., Vidua R.K. Cocaine Cardiac Toxicity: Revisited [Internet]. Open Access Peer-reviewed Chapter [Submitted: May 11th 2018; Reviewed: July 4th 2018; Published: November 5th 2018]. Available from:; DOI: 10.5772/intechopen.79929

The Drug Abuse Warning Network. Highlights of the 2010 Drug Abuse Warning Network (DAWN) Findings on Drug-Related Emergency Department Visits. Substance Abuse and Mental Health Services Administration [Accessed: September 2012]. Available from:

Richards J.R., Garber D., Laurin E.G. [et al.]. Treatment of cocaine cardiovascular toxicity: a systematic review. Clinical Toxico­logy (Phila). 2016. Vol. 54. № 5. Р. 345-364.

WADA. Всемирный антидопинговый кодекс. Международный стандарт. Запрещенный список 2019 года [Internet] / Субстанции и методы, запрещенные все время (как в соревновательный, так и во внесоревновательный период): S6. Стимуляторы [Список вступил в силу 1 января 2019 года]. Available from:

Zimmerman J.L. Cocaine intoxication. Critical. Care Clinics. 2012. Vol. 28. № 4. Р. 517-526.



How to Cite

Kursov, S. (2021). Cocaine intoxication. EMERGENCY MEDICINE, 16(5), 33–44.




Most read articles by the same author(s)

1 2 3 4 > >>