The use of dexketoprofen in modern approaches to multimodal analgesia


  • V.V. Nikonov Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine, Kharkiv, Ukraine
  • K.I. Lyzohub Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine, Kharkiv, Ukraine
  • M.V. Lyzohub State Institution “Sytenko Institute of Spine and Joint Pathology of the National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine



pain control, multimodal analgesia, opioids, dexketoprofen


One of the priority tasks in the management of patients in the intraoperative and early postoperative period is appropriate pain control, which provides not only a smooth clinical course of the disease and quality of life of patients, but also the success of surgical treatment in general by reducing the number of stress complications. Prolonged postoperative acute pain can cause the development of functional disorders of the lungs, cardiovascular system, gastrointestinal tract, central nervous system, hemostasis system, etc. The use of opioids increases the number of complications in the early postoperative period. Therefore, today a promising area is the use of multimodal analgesia, which promotes better pain relief, a smoother clinical course, early mobilization of patients by minimizing the number of complications caused by opioids. The choice of an adequate model of postoperative analgesia should be based on an understanding of the multifaceted nature of the pain syndrome, which may include both the somatic component due to surgical trauma and neuropathic one caused by chronic inflammation, neuropathy, ischemic disorders. The article presents data from current researches on the concept of multimodal analgesia, which shows that the use of dexketoprofen (Dexpro) as its part promotes better and longer analgesia, prevents the development of chronic postoperative pain, reduces the need for narcotic analgesics.


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How to Cite

Nikonov, V., Lyzohub, K., & Lyzohub, M. (2021). The use of dexketoprofen in modern approaches to multimodal analgesia. EMERGENCY MEDICINE, 16(5), 28–32.




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