The role of balanced solutions in physician’s practice


  • K.I. Lyzohub Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine, Kharkiv, Ukraine
  • V.V. Nikonov Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine, Kharkiv, Ukraine
  • M.V. Lyzohub State Institution “Sytenko Institute of Spine and Joint Pathology of the National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine



infusion therapy, balanced crystalloid solution, Plasmoven®, saline solution, hypovolemia, review


Infusion therapy plays a major role in the treatment of patients in the prehospital stage, in the intensive care units, in the perioperative and postoperative period. When calculating the required volume of fluid therapy, many factors are taken into account: from which solution to start fluid resuscitation (quantitative and qualitative composition of the solution), the required volume, rate and target indicators that determine the adequacy of fluid resuscitation. To date, there is no ideal solution for infusion therapy, but there are attempts to improve the solutions, especially by reducing complications. Historically, saline (0.9% sodium chloride) is the most commonly used intravenous solution, but the consequences of its application are significant: renal dysfunction, hyperchloremic acidosis, dilution acidosis. Balanced crystalloids have become a worthy replacement for saline, the main feature is the reduction of complications during their use, including iatrogenic, which improves the clinical condition of patients. In Ukraine, a balanced isoplasmic crystalloid Plasmoven®, which meets the requirements of ideal saline, is the optimal choice for patients with hypovolemia, burn disease, pancreatitis, trauma, in the peri- and postoperative period.


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How to Cite

Lyzohub, K., Nikonov, V., & Lyzohub, M. (2021). The role of balanced solutions in physician’s practice. EMERGENCY MEDICINE, 16(5), 17–21.



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