Features of intensive care of patients with diabetic ketoacidosis during the pandemic COVID-19


  • O.A. Halushko Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0001-7027-8110
  • I.A. Kuchynska Shupyk National University of Public Health of Ukraine, Kyiv, Ukraine; Universal Clinic “Oberig”, Kyiv
  • S.I. Babak Kyiv Regional Clinical Hospital, Kyiv, Ukraine
  • V.V. Yurkiv Kyiv Regional Clinical Hospital, Kyiv, Ukraine
  • L.V. Antonyuk Universal Clinic “Oberig”, Kyiv
  • M.V. Kushnyr Universal Clinic “Oberig”, Kyiv




diabetes mellitus, diabetic ketoacidosis, COVID-19, intensive care


The article analyzes the mechanisms of development and clinical manifestations of diabetic ketoacidosis (DKA), presents an intensive care program, discusses the prospects for the use of infusions based on xylitol in the treatment of DKA. The authors presented their own experience of using a solution with a 5% xylitol. It was shown that the use of xylitol can have a positive effect on various parts of the pathological process — from the elimination of dehydration to the correction of acid-base disorders. The authors also discuss the causes of severe ketoacidosis in patients with COVID-19 and present their own experience in the treatment of 14 patients with DKA on the background of COVID-19.


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Karslioglu French E., Donihi A.C., Korytkowski M.T. Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients. BMJ. 2019, May 29. 365. l1114. doi: 10.1136/bmj.l1114.

Chaithongdi N., Subauste J.S., Koch C.A., Geraci S.A. Diagnosis and management of hyperglycemic emergencies. Review. Hormones. 2011. 10(4). 250-260.

Palmer B.F., Clegg D.J. Electrolyte and Acid-Base Disturbances in Patients with Diabetes Mellitus. N. Engl. J. Med. 2015. 373. 548-59. doi: 10.1056/ NEJMra1503102 pmid:26244308.

Шлапак І.П., Маньковський Б.М., Галушко О.А., Кондрацька І.М. Інфузійна терапія в практиці лікаря-ендокринолога. К., 2016. 294 с.

Halushko O., Loskutov O., Kuchynska I., Synytsyn M., Boliuk M. The main causes of the complicated course of COVID-19 in diabetic patients (review). Georgian Medical News. 2020. № 10(307). 114-120.

Маньковський Б.М., Галушко О.А. Чому хворі на цукровий діабет мають гірші результати в лікуванні COVID 19? (аналітичний огляд і практичні рекомендації). Здоров’я суспільства. 2020. Т. 9. № 2. 37-45.

Nyenwe E.A., Kitabchi A.E. The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management. Metabolism. 2016. 65. 507-521. doi: 10.1016/j.metabol.2015.12.007 pmid:26975543.

Chiasson J.L., Aris-Jilwan N., Bélanger R., Bertrand S., Beauregard H., Ekoé J.M., Fournier H., Havrankova J. Diagnosis and treatment of diabetic ketoacidosis and the hyperglycaemic hyperosmolar state. CMAJ. 2003, Apr 1. 168(7). 859-866.

Joint British Diabetes Societies Inpatient Care Group. The management of diabetic ketoacidosis in adults. 2nd edition. 2013. http://www. diabetologists-abcd.org.uk/JBDS/JBDS_IP_DKA_Adults_Revised.pdf.

American Diabetes Association. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes-2019. Diabetes Care. 2019 Jan. 42(Suppl. 1). 173-181. doi: 10.2337/dc19-S015.

Кучинська І.А., Бондар М.В., Арешніков Д.Б., Шаповал С.С., Добуш Р.Д. Застосування принципів бриджинг-терапії при супутній гострій печінковій недостатності. Медицина неотложных состояний. 2016. № 3(74). 112-116.

Тронько Н.Д., Соколова Л.К., Рыбченко Ю.Б. Неотложные состояния в диабетологии: кетоацидотическая кома. Острые и неотложные состояния в практике врача. 2008. 4. 25-28.

Chua H.R., Schneider A., Bellomo R. Bicarbonate in diabetic ketoacidosis — a systematic review. Ann. Intensive Care. 2011. 1.23. doi: 10.1186/2110-5820-1-23 pmid:21906367.

Бокарев И.Н., Великов Б.К., Шубина О.И. Сахарный диабет. Руководство для врачей. М.: ООО «Медицинское информационное агентство», 2006. 400 с.



How to Cite

Halushko, O., Kuchynska, I., Babak, S., Yurkiv, V., Antonyuk, L., & Kushnyr, M. (2021). Features of intensive care of patients with diabetic ketoacidosis during the pandemic COVID-19. EMERGENCY MEDICINE, 17(2), 129–135. https://doi.org/10.22141/2224-0586.17.2.2021.230663



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