Current Approaches to the Correction of Hemostasis in Surgeries for Giant Uterine Myoma
DOI:
https://doi.org/10.22141/2224-0586.8.71.2015.79203Keywords:
giant uterine myoma, blood loss, fibrinolysisAbstract
The objective of the study was to reduce the perioperative blood loss in patients with giant uterine myoma. As a result of studies, we have obtained evidence that the use of antifibrinolytic therapy as intravenous infusion of tranexamic acid 30 minutes before the surgery in a dose of 20 mg/kg followed by infusion of 5 mg/kg per hour for the first postoperative day helped to reduce perioperative blood loss by 29 %. In patients of the second group, hemoglobin level on the second postoperative day was higher by 10 % (p < 0.05), blood loss was lower by 29 % (p < 0.05), the length of stay in hospital was reduced by 24 % (p < 0.05).
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Copyright (c) 2016 O.O. Tarabrin, D.H. Havrychenko, S.S. Shcherbakov, H.I. Mazurenko, O.V. Turenko, K.P. Kirpichnikova
This work is licensed under a Creative Commons Attribution 4.0 International License.