Perioperative Analgesia at Appendectomy: Dexketoprofenum versus Rofecoxibum

Authors

  • O.Yu. Boduliev HSEI «Ukrainian Medical Stomatological Academy», Poltava; SI «Regional Clinical Hospital of the Poltava Station» of the STBA «Southern Railway»

DOI:

https://doi.org/10.22141/2224-0586.3.74.2016.77586

Keywords:

postoperative analgesia, dexketoprofenum, rofecoxibum, appendectomy

Abstract

The effectiveness of perioperative analgesia with dexketoprofenum and rofecoxibum as medications for basic therapy in patients undergone appendectomy was compared in the work. The level of pain by the Visual Analogue Scale, necessity of additional analgesia and self-assessment of the analgesia quality by a patient were investigated. As a result the better quality of analgesia with Dexketoprofenum in the examined group of patients was registered, probable due to inhibition of COX-1 in the tissues of post-operative wound.

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References

Ванданов Б.К. Изменения цитокинового статуса больных, оперированных в условиях общей и сочетанной анестезии / Ванданов Б.К., Тимербаев В.Х., Лебедев Н.Н. // Новости анестезиологии и реаниматологии. — 2009. — № 1. — ​С. 99.

Комкин В.А Оптимизация послеоперационного обезболивания с позиции контроля воспалительного ответа у пациентов ортопедического профиля / Комкин В.А., Жирова Т.А., Руднов В.А. // Фундаментальные исследования. — 2013. — № 7 (ч. 1). — ​С. 105-108.

Girish P. Joshi. Procedure-specific pain management: the road to improve postsurgical pain management? / Girish P. Joshi, Kehlet H. // Anesthesiology. — 2013. — № 118(4). — ​Р. 780-782.

Kehlet H. Prospect Working Group. PROSPECT: evidence-based, procedure-specific postoperative pain management / H. Kehlet, R.C. Wilkinson, H.B. Fischer // Best practice & research clinical anaesthesiology. — 2007. — ​Vol. 21, № 1. — ​P. 149-159.

Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management / Apfelbaum J.L., Ashburn M.A., Connis R.T. et al. // Anesthesiology. — 2012. — № 116(2). — ​Р. 248-273.

Simon D.L. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition / Simon D.L., Botting R.M., Hla T. // Pharmacol. Rev. — 2004. — № 56. — ​Р. 387-437.

Published

2022-01-27

How to Cite

Boduliev, O. (2022). Perioperative Analgesia at Appendectomy: Dexketoprofenum versus Rofecoxibum. EMERGENCY MEDICINE, (3.74), 144–146. https://doi.org/10.22141/2224-0586.3.74.2016.77586

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Section

Original Researches

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