The first experience of using multimodal low-opioid anesthesia for coronary artery bypass surgery

Authors

  • О.A. Loskutov Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of Ministry of Health of Ukraine”, Kyiv, Ukraine
  • T.A. Danchyna Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine National Military Medical Clinical Center “Main Military Clinical Hospital”, Kyiv, Ukraine
  • V.G. Kolesnykov Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of Ministry of Health of Ukraine”, Kyiv, Ukraine
  • A.M. Druzhina Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine State Institution “Heart Institute of Ministry of Health of Ukraine”, Kyiv, Ukraine
  • N.V. Korotchuk State Institution “Heart Institute of Ministry of Health of Ukraine”, Kyiv, Ukraine
  • O.O. Bugai National Military Medical Clinical Center “Main Military Clinical Hospital”, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0586.2.89.2018.126607

Keywords:

anesthesia, coronary artery bypass surgery, multimodal low-opioid anesthesia

Abstract

The article deals with the study on the effectiveness of multimodal low-opioid anesthesia during coronary artery bypass surgery. The study included 11 patients aged 69.5 ± 6.2 years, who underwent coronary artery bypass surgery. All patients were operated under general anesthesia. The average duration of anesthesia was 257.4 ± 19.1 min. Induction included propofol (1.52 ± 0.05 mg/kg), fentanyl (1–1.5 μg/kg), pipecuronium bromide (0.1 mg/kg). Maintenance of anesthesia: sevoflurane (1.5–2 minimum alveolar concentration), keta­mine (0.5 mg/kg), lidocaine 1 mg/kg bolus, with continuous infusion (1.5–2 mg/kg/h). The average dose of fentanyl used for the entire period of anesthetic management was 1.09 ± 0.03 μg/kg/h (358.3 ± 27.1 μg during surgery). The researches have shown that multimodal low-opioid anesthesia provides an adequate analgesic effect and allows refusing intraoperative use of high doses of narcotic analgesics when performing highly traumatic operations, which is confirmed by the absence of hemodynamic and endocrine-metabolic shifts during its use.

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Published

2018-04-30

How to Cite

Loskutov О., Danchyna, T., Kolesnykov, V., Druzhina, A., Korotchuk, N., & Bugai, O. (2018). The first experience of using multimodal low-opioid anesthesia for coronary artery bypass surgery. EMERGENCY MEDICINE, (2.89), 78–83. https://doi.org/10.22141/2224-0586.2.89.2018.126607

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Section

Original Researches

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